MERSCOPE Imaging of WT, Trem2-R47H, 5xFAD and Trem2-R47H; 5xFAD samples
Open in Visualizer
Abstract
This dataset contains MERSCOPE Imaging data of 19 coronal hemispheres in WT, Trem2-R47H, 5xFAD, and Trem2-R47H; 5xFAD mice. Sections were imaged with a 300 gene panel, combined with DAPI imaging for localization of cellular nuclei.
Citation
Xu, Xiangmin. (2024). MERSCOPE Imaging of WT, Trem2-R47H, 5xFAD and Trem2-R47H; 5xFAD samples [Dataset/Microscopy]. Brain Image Library.
Specimen Information
Species
Mouse
Age
12 months
Sex
Female/Male
Organ
Brain
Location
Coronal Section
Technique
MERFISH
Contributors
Xu, Xiangmin
ProjectLeader - University of California, Irvine
Funding
National Institutes of Health
Grant: 1-R01-AG082127-01
Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions
National Institutes of Health
Grant: 1-U01-AG076791-01
Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's disease
License & Data Access
Creative Commons Attribution 4.0 International (CC BY 4.0)